Pediatric Laboratory Diagnostics
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A compilation of useful publications for the pediatric laboratory professional.

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Pediatric Reference Interval Project Publications  
Owen, W.E., Roberts, W.L., 2005 Performance characteristics of an HPLC assay for urinary albumin. Am. J. Clin. Path., 124, 219-25.
Flanders, M.M., Crist, R.A., Roberts, W.L., Rodgers, G.M., 2005, Pediatric reference intervals for seven common coagulation assays. Clin. Chem., 51, 1738-42.
Kushnir, M.M., Rockwood, A.L., Roberts, W.L., Pattison, E., Bunker, A., Meikle, A.W., 2006, Performance characteristics of a novel tandem mass spectrometric assay for serum testosterone. Clin. Chem., 52, 120-8.
Flanders, M.M., Phansalkar, A.R., Crist, R.A., Roberts, W.L., Rodgers, G.M., 2006, Pediatric reference intervals for uncommon bleeding and thrombotic disorders. J. Peds., 149, 275-7.
Kushnir, M.M., Rockwood, A.L., Roberts, W.L., Pattison, E.G., Owen, W.E., Bunker, A.M., Meikle, A.W., 2006, Development and performance evaluation of a novel tandem mass spectrometry assay for four adrenal steroids. Clin. Chem., 52, 1559-67.
Biochemical Genetics  
Russo PA, Mitchell GA, Tanguay RM. Tyrosinemia: a review. Pediatr Dev Pathol. 2001 May-Jun;4(3):212-21. Review.  
Clinical Pediatrics  
Celiac Sprue - NEJM, Vol 346 (No.3), Janu 17, 2002  
Schilling FH, Spix C, Berthold F, Erttmann R, Fehse N, Hero B, Klein G, Sander J, Schwarz K, Treuner J, Zorn U, Michaelis J. Neuroblastoma screening at one year of age. N Engl J Med. 2002 Apr 4;346(14):1047-53  
Olson RE. The role of dietary and plasma lipids in childhood atherogenesis. Pediatr Pathol Mol Med. 2002 Mar-Apr;21(2):137-52  
Zieske AW, Malcom GT, Strong JP. Natural history and risk factors of atherosclerosis in children and youth: the PDAY study.Pediatr Pathol Mol Med. 2002 Mar-Apr;21(2):213-37  
Cytogenetics  
Xiao S, Renshaw A, Cibas ES, Hudson TJ, Fletcher JA. Novel fluorescence in situ hybridization approaches in solid tumors. Characterization of frozen specimens, touch preparations, and cytological preparations. Am J Pathol. 1995 Oct;147(4):896-904.  
Epidemiology  
Hoffenberg EJ, MacKenzie T, Barriga KJ, Eisenbarth GS, Bao F, Haas JE, Erlich H, Bugawan Tl T, Sokol RJ, A prospective study of the incidence of childhood celiac disease. J Pediatr. 2003 Sep;143(3):308-14.  
Infectious Diseases  
Hall CB. Respiratory syncytial virus and parainfluenza virus. N Engl J Med. 2001 Jun 21;344(25):1917-28. Review.  
Wick MJ, Woronzoff-Dashkoff KP, McGlennen RC. The molecular characterization of fatal infectious mononucleosis. Am J Clin Pathol. 2002 Apr;117(4):582-8  
Microbiology  
Jones RN; College of American Pathologists Microbiology Resource Committe. Method preferences and test accuracy of antimicrobial susceptibility testing: updates from the College of Amercian Pathologists Microbiology Surveys Program. Arch Pathol Lab Med. 2001 Oct;125(10):1285-9  
 
Molecular Genetics  
Hofgrtner WT, Tait JF. Frequency of problems during clinical molecular-genetic testing. Am J Clin Pathol. 1999 Jul;112(1):14-21  
Kushner BH, LaQuaglia MP, Cheung NK, Kramer K, Hamelin AC, Gerald WL, Ladanyi M. Clinically critical impact of molecular genetic studies in pediatric solid tumors. Med Pediatr Oncol. 1999 Dec;33(6):530-5  
Naito N, Kawai A, Ouchida M, Dan'ura T, Morimoto Y, Ozaki T, Shimizu K, Inoue H. A reverse transcriptase-polymerase chain reaction assay in the diagnosis of soft tissue sarcomas. Cancer. 2000 Nov 1;89(9):1992-8  
Ladanyi M, Bridge JA. Contribution of molecular genetic data to the classification of sarcomas. Hum Pathol. 2000 May;31(5):532-8. Review.  
Lyon E, Miller C. Current challenges in cystic fibrosis screening. Arch Pathol Lab Med. 2003 Sep;127(9):1133-9.  
Sotiriou C, Khanna C, Jazaeri AA, Petersen D, Liu ET. Core biopsies can be used to distinguish differences in expression profiling by cDNA microarrays. J Mol Diagn. 2002 Feb;4(1):30-6.  
Popov P, Virolainen M, Tukiainen E, Asko-Scljavaara S, Huuhtanen R, Knuutila S, Tarkkanen M. Primary soft tissue sarcoma and its local recurrence: genetic changes studied by comparative genomic hybridization. Mod Pathol. 2001 Oct;14(10):978-84  
Florell SR, Coffin CM, Holden JA, Zimmermann JW, Gerwels JW, Summers BK, Jones DA, Leachman SA. Preservation of RNA for functional genomic studies: a multidisciplinary tumor bank protocol. Mod Pathol. 2001 Feb;14(2):116-28.  
Newborn Screening  
LeGrys VA. Newborn Screening for Cystic Fibrosis. Lab Med. 2002 Mar;3(33):212-3  
Woods WG, Gao RN, Shuster JJ, Robison LL, Bernstein M, Weitzman S, Bunin G, Levy I, et al. Screening of Infants and Mortality Due to Neuroblastoma. N Engl J Med. 2001 April 4;346(14):1041  
Pediatric Clinical Chemistry  
Ashwood ER. Standards of laboratory practice: evaluation of fetal lung maturity. National Academy of Clinical Biochemistry. Clin Chem. 1997 Jan;43(1):211-4. Review.  
Pediatric Hematology  
Collins MH, Montone KT, Leahey AM et al. Post-transplant lymphoproliferative disease in children. Pediatr Transplantation 2001;5(4):250-7.  
Yanowitz TD, Jordan JA, Gilmour H, et al. Hemodynamic disturbances in premature infants born after chorioamnionitis: Association with cord blood cytokine concentrations. Pediatr Res 2002;51(3):310-316.  
Pediatric Immunology  
Schultz C, Rott C, Temming P, Schlenke P, Moller JC, Bucsky P. Enhanced interleukin-6 and interleukin-8 synthesis in term and preterm infants. Pediatr Res 2002;51(3):317-322  
Pediatric Laboratory Medicine  
Coffin CM, Hamilton MS, Pysher TJ, Bach P, Ashwood E, Schweiger J, et al. Pediatric Laboratory Medicine: Current Challenges and Future Opportunities. Am J Clin Pathol. 2002;117:683-690
Dighe AS, Soderberg BL, Laposata M. Narrative Interpretations for Clinical Laboratory Evaluations. An Overview. Am J Clin Pathol. 2001;116(Suppl 1):S123-S128  
MacMillan DH, Soderber BL, Laposata M. Regulations Regarding Reflexive Testing and Narrative Interpretations in Laboratory Medicine. Am J Clin Pathol. 2001;116(Suppl 1):S129-S132  
Kratz A, Soderberg BL, Szczepiorkowski ZM, Dighe AS, Versalovic J, Laposata M. The Generation of Narrative Interpretations in Laboratory Medicine. Am J Clin Pathol. 2001;116(Suppl 1):S133-S140  
Pediatric Surgical Pathology  
Jones D, Fletcher CD. How shall we apply the new biology to diagnostics in surgical pathology? J Pathol. 1999 Jan;187(1):147-54. Review.  
Point-of-Care Testing  
Kost GJ. Preventing medical errors in point-of-care testing: security, validation, safeguards, and connectivity.. Arch Pathol Lab Med. 2001 Oct;125(10):1307-15